A life-threatening allergic reaction. Massive amounts of histamine and other chemicals are released, causing immediate changes to body tissues: the blood vessels dilate causing a sudden lowering of blood pressure, and swelling of the tongue and airways occurs. Peanuts, shellfish and bee stings are common culprits. Tryptase is an enzyme released during anaphylaxis, which can be measured on a blood test to confirm that this type of allergic reaction has definitely occurred.